Grey’s Anatomy
Summary
Izzie Stevens ( Katherine Heigl ) and Alex Karev ’s ( Justin Chambers ) complicated , recollective - term kinship is one of the most memorable love thing inGrey ’s Anatomy . At first , their romance is unexpected , as they do n’t get along as houseman at Seattle Grace Hospital , but the lineament both come in from broken homes and share a desire to become successful Dr. . Grey ’s Anatomyis know for featuring characters who fall in love as a result of the propinquity of act upon together , but there ’s something special and heartfelt about this particular duad . Their obstacles and disputation make up some of the most unforgettable moments in the long - run medical dramatic play .
While the series largely centre onMeredith Grey and Derek Shepherd ’s Latinian language , Izzie and Alex have a significant love story as well . They separate for a large portion of theGrey ’s Anatomytimeline but do encounter their manner back together . While Meredith ( Ellen Pompeo ) has to say goodbye to her soulmate Derek ( Patrick Dempsey ) , Izzie and Alex eventually have a happy ending , although one that is just as emotional as the rest of their interactions .
Season 1, Episode 1, “A Hard Day’s Night”
Izzie And Alex Meet As Interns
In the pilot episode ofGrey ’s Anatomy , Izzie , Alex , Meredith , George O’Malley ( T.R. Knight ) , and Cristina Yang ( Sandra Oh ) converge as interns . Most of the focus is on Meredith since the series is built around her character reference , and finally , her syndicate , hence the title . By wing , Cristina gets a focus since she is Meredith ’s " person . " George , Izzie , and Alex , however , also get abbreviated introduction in the pilot before their characters are expand upon during the rest of the first season .
There is no indication that there are any Dame Muriel Spark between Alex and Izzie . They both come along a little inhuman and focused on their new careers , and they do n’t take the time to get to know each other . This first impression is significant as in a few episodes , Izzie and Alex will see each other in a different light , which will let them to bond .
Grey ’s Anatomy ’s pilot episode has one dear fiber that was digitally add : Justin Chamber ’s Alex Karev . Here ’s what materialize .
Season 1, Episodes 2-9
Izzie And Alex Focus On Their Internships, He Exposes Her Modeling Photos
In season 1 , episode 2 , " The First Cut is the Deepest,“Izzie show up she can be a just doctorwhen she work on her first large case . Alex and Izzie do n’t interact much for a few episodes , but in episode 4 , " No Man ’s Land , " he reveals photo of Izzie as a intimate apparel model for Bethany Whisper to the hospital . Izzie present her strength in being proud of bring in money to sustain herself through medical school while Alex realizes he should n’t be so judgmental and immature .
The release of Izzie ’s exposure by Alex is n’t precisely a turning stage for their characters , but it does plant the ejaculate of a connectedness between them as they both learn from the experience . Though Izzie and Alex continue to pettifog during these episode , Alex also go to see Izzie ’s confidence in her power .
Season 2, Episodes 1-3
Alex And Izzie Bond And Work Together
In season 2 , episode 1 , " Raindrops Keep Falling on My Head , " Alex and Izzie commence romance with each other . Their flirtations lead to them working better together as well . She helps him see that it ’s a smart musical theme to show patients more compassionateness or else of simply focalize on diagnosing . As Alex is interested about a patient Joe ( Steven W. Bailey ) , who arrive in after suffer from an aneurism , Izzie realizes that Alex is sweet than she thought .
It ’s during this set of episode in time of year 2 that Alex start to become more than just the stereotypical big human being on campus , allowing Izzie to get to be intimate him a bit more . As they get to sleep together one another , they start to genuinely care about one another . The path to becoming one of thebestGrey ’s Anatomycouplesbegins whenthe character can no longer ignore their feelings for each other .
Season 2, Episode 4, “Deny, Deny Deny”
Alex And Izzie Have A Lackluster First Date
Although Izzie and Alex are both intelligent and ambitious people , which should give them enough in common to start a well-chosen relationship , they have a tough first date in season 2 , instalment 4 , " Deny , Deny , Deny . " Izzie is angry that Alex decides not to osculate her at the close , but he prove his refractory and secretive nature when he does n’t admit that he ’s upset about neglect his board exam .
Though they both like one another , they are n’t yet on the same page , or quick for a committed kinship . It ’s not unlike Meredith and Derek not being completely honest with one another during the early days of their human relationship . The two of them are n’t wholly ready to be vulnerable and honest with one another . It still accept them a while to get to that dot . WhileIzzie and Alex will learn to open up up to each other , this is a unsmooth gunpoint for them inGrey ’s Anatomy .
From a Post - It note marriage ceremony to a lot of separation , Meredith Grey and Derek Shepherd ’s love affair had a tumultuous timeline on Grey ’s Anatomy .
Custom image by Amanda Bruce
Season 2, Episodes 5-9
Izzie And Alex Share Their First Kiss And Are In A Happy Place
This is a turning point in Izzie and Alex ’s new relationship as she cogitate that Alex does n’t have real feelings for her , and he is frightened to be honest about what ’s going on . Alex is a devotee - favoriteGrey ’s Anatomycharacterbecause he realizes what he has done legal injury and attempt to be a better someone , and he have it away that he has to explore his intuitive feeling for Izzie . Alex starts to grow quite a bit because of his relationship with Izzie and this is where that development set out .
The Romance language seems to be going well at this point in the series
In season 2 , episode 7 , " Something To believe About " Alex becomes more courageous and buss Izzie at Emerald City Bar . They snog again at the hospital in time of year 2 , installment 8 , " Let It Be . " The romance seems to be going well at this power point in the series , though it does n’t progress particularly speedily just yet .
Grey’s Anatomy is a medical drama series revolving around surgical interns, residents, and attendings at the fictional Grey Sloan Memorial Hospital. The show features the professional and personal lives of these medical professionals, led initially by Dr. Meredith Grey, played by Ellen Pompeo. Created by Shonda Rhimes, the series highlights the complexities of medical cases while delving into the interpersonal relationships among the hospital staff.
Season 2, Episode 10, “Much Too Much”
Alex Is Unfaithful And Sleeps With Olivia
While Alex is likely raise up , he name a mistake at the start of his burgeoning relationship with Izzie that creates a big setback for the two of them . He makes the error of sleeping with Nurse Olivia Harper(Sarah Utterback ) as he ’s afraid of becoming too secretive to Izzie and having her reject him . He thinks by continuing to see other hoi polloi , he wo n’t finger as much for Izzie as he already does .
Izzie is clearly upset , and she and Alex come along to be over . However , sinceGrey ’s Anatomyis a play where every brace split up and nonplus back together several time throughout their arc , it come out likely that the couple will find a way back to each other , even at this point in the series . Alex becomes a betterGrey ’s Anatomycharacterafter this intense plotline , as he knows that he was wrong and desire to be a loyal married person for Izzie .
Season 2, Episodes 11-20
Alex And Izzie Sleep Together But Remain Broken Up
Over the next few episodes of season 2 , Alex and Izzie avoid each other at the hospital due to the hurt intuitive feeling and awkwardness that they ’re experience . They fall back on the same patterns that most of the couples in Grey ’s Anatomy do when they have a setback - avoidance and then hooking up before truly addressing their intuitive feeling . Most of their storylines are focus on the medical fount of the week instead of each other .
In season 2 , sequence 16 , " It ’s the destruction of the World " , they are afraid when a patient comes in with a turkey in their bureau and Izzie asks Alex if he will sleep with her since survival of the fittest is n’t guaranteed . That , however , does n’t have in mind that Izzie and Alex are back together . In season 2 , episode 20 , " set - Aid Covers The Bullet Hole , " Izzie has clean feelings for patient Denny Duquette(Jeffrey Dean Morgan ) , and she feel that she can move on from Alex .
Grey ’s Anatomy ’s Alex Karev started out as a polarizing character , but he went on to become of the most darling grapheme in the show ’s long chronicle .
Season 2, Episodes 21-27
Izzie And Denny Get Engaged And Denny Dies
When Izzie is assigned to Denny , there ’s an immediate connection between the two that make her take a firm step out from Alex . Izzie and Denny have a passionate and whirlwind romance while he ’s stuck in the infirmary that include a proposal . Then , she cuts his LVAD wire to ensure he is given a heart quick . Izzie ’s actions would have gotten someone fired from her position in the real populace , but Izzie is n’t fired , which is one of themost confusing Izzie plotlines onGrey ’s Anatomyas well as one of the darkest and most excited .
Izzie put on the line her vocation for Denny and is devastated when he authorize away from a slash in time of year 2 , episode 27 , " Losing My Religion . " Throughout the instalment , the master interrogates the medical intern , wanting to learn who really cut the wire , but it ’s not until after Denny dies that Izzie confesses . She feels like nothing else matters , and she chuck up the sponge her job ( though it ’s not permanent ) to save the chief from own to penalize her .
Season 3, Episode 1-Season 4, Episode 17
Izzie And Alex Are In Other Relationships
Alex and Izzie rest low up in seasons 3 and 4 ofGrey ’s Anatomyas they germinate feelings for other people . These separate family relationship reserve Izzie and Alex to originate as characters while they ’re apart from one another , allowing them to be more than simply a romantic pairing in the series .
In season 3 , Izzie and George begin seeing each other , which is problematic since he is marital to Callie Torres ( SaraRamirez).The relationship is a surprise for a lot of fansat the time since they had n’t had amatory leanings toward one another in the past . Alex falls in love with Rebecca Pope ( Elizabeth Reaser ) , who is bid Ava at first , and assist her add up to terminal figure with her stroke , not remembering anything about her sprightliness , and her rugged human relationship with her hubby Jeff ( Jason London ) . Both Alex and Izzie become vulnerable with these other the great unwashed , but something is missing , which eventually lead them back to each other .
Season 5, Episodes 1-6
Alex And Izzie Get Back Together And Alex Wonders If They Are Truly Committed
While Izzie and Denny are one of thebestGrey ’s Anatomycouplesdue to their strong spirit for each other , Izzie genuinely cares about Alex as well , and the characters reunite at the commencement of season 5 . They ’ve had some distance from one another and been capable to grow so that they can have a more meaningful human relationship . They ’ve both suffered heartbreak due to their experiences with Ava and Denny , and they ’ve both amount out the other side .
Izzie and Alex drop each other , and it ’s clear that the hamper that they mould back in season 1 when discussing that theyboth had unstable homesand uncaring parent is still inviolate . When Alex asks if they are dating other masses or just each other , this is a catalyst for their upcoming wedding , which admit them to eventually commit .
Season 5, Episodes 7-21
Izzie Is Sick, And Her Relationship With Alex Is In Jeopardy
During the next few episode of season 5 , Izzie begins " see " Denny and experience that he is still around . Izzie hallucinates Denny because she is dyingof genus Cancer , and she has sexuality with him in her hallucination . She does n’t hide her vision from Alex though , which is a sign that the two are in a better place despite the circumstances , despite a lot of fans of the show hating this particular storyline .
This is shuddery and emotional for Alex , who is afraid of losing Izzie now that he has in conclusion gotten her back , and Izzie is equally concerned about what is happening to her as she is diagnose with Stage 4 metastatic malignant melanoma . She feel a sense of pacification when she is afraid of the path forward of her , but remember all the times that she comforted patient in the same position .
It ’s no secret that the Grey ’s Anatomy doctors are not the most ethical physicians , and Izzie , in exceptional , should have been fired multiple times .
Season 5, Episode 22, “What A Difference A Day Makes”
Alex And Izzie Get Married
After find out that she has Crab , Izzie also gets another surprise . Derek proposes to Meredith , and Meredith requests Izzie ’s help with her upcoming nuptials . While Izzie is gruesome and undergo discourse , she distract herself from her unwellness by helping Meredith design her ambition wedding . It gives something convinced for Izzie to concentrate on and submit some emphasis off of Meredith . Meredith , however , makes a different decision for Izzie and Alex .
Meredith make the kind motion of permit Alex and Izzie to get married on the twenty-four hour period that she and Derek were planning to , with most of the plans that Izzie made for them inviolate , and this is one of the sweetest moments in the entire serial publication . ThisGrey ’s Anatomywedding episodeis especially muscular since the " illness and in health " vow are coming true at this very second andAlex will be a support system for his brainsick wife .
Season 5, Episodes 23-Season 6, Episode 4
Izzie Has Surgery, And The Couple Moves Into Derek’s Trailer
After Izzie choose to have surgery to murder her tumor , Alex proves that he is more comfortable speak about his emotions when he shows that he is afraid of his married woman dying , but her operation proceed well . At the first of season 6 , the couplet begin their married life by live in the laggard that Derek owns , which result in a humourous storyline as a bear approaches Alex , and he is nervous and afraid .
This is a memorable part of the duet ’s long - full term relationshipthat balances out the emphasis and sadness surrounding them . There ’s pot of drollery in the two of them in conclusion build a lifespan together after stave off their feelings for one another for so long in the show . At this point in the series , it see like everything is going in a good direction for Izzie and Alex .
Season 6, Episode 5, “Invasion”
Izzie Is Fired And Leaves Seattle
While Izzie is weigh one of thebestGrey ’s Anatomydoctorsas she is bluff , confident , and lifelike , she also makes a tidy sum of mistakes . cut Denny ’s LVAD wire is n’t the only one , though it ’s certainly one of the most memorable . While that conclusion , and Denny ’s death , led to her quit her job for a while , season 6 sees Izzie make another dear mistake - one that harms a patient .
At the offset of season 6 , she mess up a patient ’s dialysis , which ensures that she wo n’t be able-bodied to receive a kidney , and Izzie lose her business because of the dearly-won error . This mistake is also the catalyst for the goal of her kinship with Alex , as instead of talking to her hubby about what has happened and tilt on him for support , she founder his centre and decides to lead Seattle where he has a growing career .
The determination seemed to come too quick for fans , but it was mostly due to the decision for Katherine Heigl to get out the serial publication , and Izzie did get to come back to conclude out her storyline .
Since Grey ’s Anatomy has been on the airwave for so long , it makes signified that many cast members have come in and gone , but not all left on their own pact .
Season 6, Episodes 6-11
Alex Worries, Izzie Comes Back, And The Couple Has Problems
While Izzie is by , Alex has to pay for her time in the hospital during her malignant neoplastic disease recovery , which punctuate his responsible for fibre and her impulsive behavior . Their purpose have somewhat reversed liken to when they first began to connect in the first season ofGrey ’s Anatomy . This is decidedly a modification from what the hearing might have expected when they were first introduced to the characters , and it ’s one of the reasons Alex became such a fan - favorite . His maturation is so much more evident than some of the other characters .
When Izzie comes back in season 6 , episode 9 , " New chronicle , " Alex has too much resentment to forgive her . This is n’t just a unsmooth patch for the two of them as Izzie left without a word and leave Alex to take care of her debt . She ca n’t plainly make him see . It ’s clean that Izzie and Alex are over at this full point in the serial publication .
Season 6, Episode 12, “I Like You So Much Better When You’re Naked”
Alex Ends The Relationship With Izzie, And She Leaves For Good
Izzie leavesGrey ’s Anatomyin season 6after attempting to fix her human relationship with Alex . As much as she appears to want to fix things , Alex can not see a path forward . Alex shares his desire for a loving , compassionate , loyal person who he can look on and get Izzie know that their beloved story is over because they have n’t been able-bodied to be that for each other . Even though they intelligibly care about one another , jazz one another is n’t enough to make their human relationship work , and right now , they can not put in the exploit required to do that .
What happens to Izzie next is leave a mystery for several season , but it ’s clear that Alex has learned a peck about trusting people and making indisputable that his next partner is n’t exit to lam whenever something work incorrect . While he does n’t rush into another relationship , Alex is capable to translate what he wants , what he merit , and how to put in the work .
Season 6, Episode 13-Season 12, Episode 2
Alex Moves On And Commits To Jo
Without Izzie , Alex ab initio focuses on his career . He evolve feelings for fellow physician Lucy Fields ( Rachael Taylor ) in season 7 and becomes close to Meredith . In fact , he and Meredith really become one another ’s confidante without Izzie and Cristina around . Alex slowly moves on with his life , no longer focusing on the pain in the neck Izzie make him .
However , it ’s in season 9 that he falls in love with Jo Wilson ( Camilla Luddington ) . The two doctors step by step get their family relationship and become serious in season 11 and 12 . Jo and Alex have their own portion of issues to share with , most of which come from Jo possess to work on psychic trauma from her own past , which she is able-bodied to do . Although it appears that Alex is glad and has met his true mate with Jo , his yesteryear with Izzie is about to get back to frequent him in season 12 .
Season 12, Episode 3, “I Choose You”
Jo Learns Alex And Izzie Could Have Children Together
AlthoughJo appear dead equalise for Alex , she realizes that a kinship between her and Alex might not work out after all . Alex has been keep on a enigma from her , and it ’s one that no one else has have it away about since he and Izzie initially got marry . Jo discovers that Alex might be the father of Izzie ’s children when she discover out that Alex has been paying for embryos belong to Izzie at a rankness clinic .
Izzie and Alex had decided to freeze embryos when she was sick , just in case anything went wrong with her treatment so that they could still have children in the futurity , something he had n’t severalise Jo . While Alex attempt to continue calm and get Jo know that she should bury about it , Jo , who has had a hard life include an abusive marriage ceremony , is afraid of being left behind . The serial hints at how Izzie could threaten Alex ’s new relationship at this point in time despite Izzie having been run from the show for six years .
While for some fans , it might have seemed like a convenient way to cast off a wrench into the relationship between Alex and Jo , it was a suggestion that Alex might not truly be as over Izzie as he conceive himself to be . After all , he ’s still the one pay for the reposition of the embryos .
Season 12, Episodes 4-Season 16, Episode 15
Alex And Jo Get Married And Have A Happy Relationship
Alex and Jo make up and continue their peaceable human relationship through season 12 and 13 . For multiple seasons , it come out that the prickteaser about Izzie potentially having Alex ’s children is just forget . Alex and Jo are at such a good place in their relationship that they even get marry in season 14 , episode 24 , " All Of Me . " They have a good marriage , as Alex has become true in the years since Izzie moved away ; he is now capable of being the stable better half that he always wanted to be .
Alex ’s relationship with Jo show that the growth he go through while inhis kinship with Izzie was n’t going to be shortlived . His human relationship with Izzie , even though it end in heartbreak , made him a well person . It allowed him to be one of the characters to get the most growth in the serial publication and to have healthier approaches to the women in his lifetime .
One of the most late and controversial release from Grey ’s Anatomy was that of Alex Karev , and here ’s why his goodbye was n’t well - received .
Season 16, Episode 16, “Leave A Light On”
Alex Learns Izzie Is Raising Their Kids And Moves To Be With Them
He make a drastic conclusion about his life
Alex and Izzie ’s unpopular finalGrey ’s Anatomystorylinesees Alex phoning Izzie after indite a alphabetic character of recommendation for Meredith and remembering the glad times of the past tense . When he can listen children in the background , he study that she is stir their twins Eli and Alexis . It ’s instruct that he has a menage that gives Alex interruption . After reconnecting with Izzie and meeting his children , he pass water a drastic decision about his life history .
This major decision is , of course , influenced by the decisiveness of Justin Chambers to leaveGrey ’s Anatomyafter playing Alex Karev for 16 class . Fans were distressing to see him go , and the series write him out in a very disconnected way .
Meredith read a varsity letter Alex wrote her and learns he depart Jo so that he could entrust to Izzie . While Alex and Izzie are both happy about this determination , it was a bold move for the series , and the twain ’s felicitous finish is marred by Jo ’s grief . After so many ups and pile , Izzie and Alex end up together off - screen door inGrey ’s Anatomywhile Jo is left to move on . It ’s unlikely that the series will ever bring back Izzie or Alex since both actors chose to walk off from the serial and both characters had such drastic exits .
Your Rating
Your gossip has not been saved
Cast
Grey ’s Anatomy is a aesculapian dramatic play serial revolve around surgical interns , residents , and attendings at the fabricated Grey Sloan Memorial Hospital . The show feature the professional and personal lives of these medical professional , led ab initio by Dr. Meredith Grey , played by Ellen Pompeo . Created by Shonda Rhimes , the series highlight the complexities of medical cases while delving into the interpersonal relationships among the hospital staff .
